Skip to main content
. Author manuscript; available in PMC: 2019 Mar 1.
Published in final edited form as: Am J Reprod Immunol. 2017 Nov 30;79(3):10.1111/aji.12790. doi: 10.1111/aji.12790

Figure 3. Senescence-associated inflammatory cytokine IL-6.

Figure 3

TNF-α treated amnion cells increased the inflammatory cytokine IL-6 when compared to untreated cells. This effect was down-regulated when co-treated with SB203580, confirming a p-38 mediated effect. LPS treatment also increased IL-6, to a lesser degree. This effect was reduced with SB203580 co-treatment. Amnion cells exposed to CSE increased the inflammatory cytokine IL-6; however, not significantly. Co-treatment with SB203580 decreased IL-6 production.