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. Author manuscript; available in PMC: 2019 Feb 1.
Published in final edited form as: Spine J. 2017 Oct 12;18(2):343–356. doi: 10.1016/j.spinee.2017.09.018

Figure 5. Percent positivity of macrophage phenotype markers significantly increased in NP and EP but not AF regions.

Figure 5

The percentage of cells immunopositive for CCR7, CD163, and CD206 were averaged within NP, AF, and EP regions for individual IVDs and correlated with Rutges degenerative grade. CCR7+, CD163+ and CD206+ cells all significantly increased with degenerative grade in endplate (EP) regions while only CCR7+ cells significantly increased in NP regions. No changes in percent positivity of any macrophage marker were observed with degenerative grade in AF regions. (N = 12). R = Spearman’s correlation coefficient (95% Confidence Interval).