Skip to main content
. Author manuscript; available in PMC: 2019 Mar 1.
Published in final edited form as: Wiley Interdiscip Rev RNA. 2017 Dec 27;9(2):10.1002/wrna.1459. doi: 10.1002/wrna.1459

Figure 1. Glucose homeostasis in Type 1 and Type 2 diabetes.

Figure 1

Pancreatic beta-islet cells secrete insulin to control glucose levels in the blood. Insulin allows glucose absorption into target tissues that include skeletal muscle, adipose tissue and liver to maintain normal glucose levels in the blood. In Type 1 diabetes, blood glucose levels increase because insulin is production is reduced due to the destruction of beta-islet cells in the pancreas. In Type 2 diabetes, insulin resistance prevents the efficient uptake of glucose into target tissues causing hyperglycemia.