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. 2018 Feb 12;5:6. doi: 10.3389/fnut.2018.00006

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Copyright © 2018 Bowtell, Mohr, Fulford, Jackman, Ermidis, Krustrup and Mileva.

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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EMG responses to peripheral nerve stimulation in fresh and fatigued musculus vastus medialis. Population average (±SEM, n = 9) peak-to-peak amplitude (A,B) and total area (C,D) of the maximal compound muscle action potentials (Mmax) were calculated from the EMG responses evoked by suprathreshold (130% Mmax) femoral nerve stimulation. The femoral nerve was stimulated with five single pulses at rest (A,C) and during maximal voluntary contractions (B,D) performed before (PreEx) and after (PostEx) the completion of the exercise protocol to task failure. The exercise was conducted 1 h after ingestion of either caffeine (filled bars) or placebo (empty bars) supplement; ^$condition × time interaction effect, p < 0.05.