Skip to main content
. 2018 Jan 30;115(7):1499–1504. doi: 10.1073/pnas.1721967115

Fig. 5.

Fig. 5.

MALT1 and TRAF6 cooperatively assemble with BCL10 filaments. (A) A cryo-EM micrograph of the BCL10–MALT1 complex filaments. (B) MALT1 interaction with CARMA1–BCL10 filaments by microfluidics. (C–E) Micrographs of negatively stained samples containing, respectively, 1:1 molar ratio of MALT1 to BCL10 (C), 1:10 molar ratio of MALT1 to BCL10 (D, Left), 1:20 molar ratio of MALT1 to BCL10 (Right), BCL10 alone (E, Left), CBM complex (Center), and CBM–TRAF6 complex (Right). BCL10-alone and BCL10–MALT1 complex filaments coexist on the same micrograph (D) and the approximate diameters of the different filaments are shown (E).