Fig. 1.

Schematic and the components of the hydrostatic pressure bioreactor system. The system (a) consists of a bioreactor chamber connected to the servo stimulator placed within an incubator (Adapted from Reinwald et al. [23]) (b). The chamber can hold a standard tissue culture plate (c). To apply HP to the samples within the bioreactor chamber, compressed incubator air is pumped into the bioreactor chamber via an air heater. The stimulation regime is applied via a growthworks control box and laptop accompanied by growthworks software.