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. 2018 Feb 17;6:35. doi: 10.1186/s40168-018-0417-4

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© The Author(s). 2018

Open AccessThis article is distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated.

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Fig. 1 — T1D-susceptible NOD mice share similarities in their gut microbiota which is animal facility independent. a Stacked bar graphs show top 21 genera present in individual mice. b sPLS-DA multivariate analysis. c Differences in individual genera, see also Additional file 1: Figure S2. FDR adjusted p values are shown from PERMANOVA testing. d NOD/Lt and B6 mice (BRF) were cohoused during pregnancy until weaning. Co-housed offspring were sampled at 12 weeks of age for fecal microbiota analysis as in a. Control single-strain-housed NOD/Lt and B6 mice (BRF) are shown in a. See also Additional file 1: Figures S1 and S3