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. 2018 Feb 17;37:5. doi: 10.1186/s40101-018-0165-y

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© The Author(s). 2018

Open AccessThis article is distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated.

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Fig. 2 — The morphology of rat heart tissues exposed to hypoxia for 1, 3, and 7 days. Control group: myocardial structure was normal, myocardial cells arranged in parallel, the nucleus was located in the center. Hypoxia-1 group: myocardial fiber arrangement was normal, but there were some inflammatory cell infiltration and muscle cell nucleus shrinkage and apoptosis. Hypoxia-3 group: there were mild myocardial fiber arrangement disorder, widened myocardial interstitium, cell edema, loose cytoplasm, rounded nucleus, and increased interstitial blood vessels. Hypoxia-7 group: there were severe myocardial fiber arrangement disorder, severe muscle fiber bundle damage, and large number of muscle cell necrosis; muscle cell boundary was unclear. HE staining (× 400)