Table 4.

Genotypes of the two DOCK7-ANGPTL3 SNPs and the risk of CAD and IS

SNP/Model	Ref. Genotype	Effect Genotype	(OR 95% CI)CAD	P CAD	IS (OR 95% CI)IS	P IS
rs1748195
Codominant	CC	CG	1.16 (0.88-1.54)	0.058	0.93 (0.69–1.6)	0.221
		GG	1.90 (1.10–3.29)		1.59 (0.89–2.84)
Dominant	CC	CG/GG	1.25 (0.96–1.64)	0.098	1.01 (0.76–1.35)	0.933
Recessive	CC/CG	GG	1.79 (1.04–3.06)	0.017	1.63 (0.92–2.88)	0.092
Overdomiant	CC/GG	CG	1.09 (0.83–1.43)	0.552	0.89 (0.66–1.19)	0.439
Log–additve	–	–	1.27 (1.02–1.57)	0.014	1.09 (0.87–1.37)	0.450
Rs12563308
Codominant	TT	CT	0.67 (0.44–1.03)	0.192	0.75 (0.48–1.16)	0.408
		CC	1.17 (0.17–7.99)		1.28 (0.15–11.62)
Dominant	TT	CT/CC	0.69 (0.45–0.94)	0.011	0.76 (0.49–1.17)	0.206
Recessive	TT/CT	CC	1.23 (0.18–8.44)	0.834	1.33 (0.15–11.62)	0.799
Overdomiant	TT/CC	CT	0.67 (0.44–1.03)	0.068	0.75 (0.48–1.16)	0.187
Log–additve	–	–	0.73 (0.49–0.89)	0.009	0.79 (0.53–1.19)	0.264

SNP single nucleotide polymorphisms, CAD coronary artery disease, IS ischemic disease, OR (95%CI) Odds ratio (OR) and 95% confidence interval (CI) between patients and controls