Table 1.
Patient, infection, and pathogen characteristics among critically ill patients with bloodstream infection
| Characteristica | N (%), Median (IQR) |
|---|---|
| Patient characteristic | |
| Male sex | 63 (55) |
| Age in years | 67 (57–78) |
| APACHE II Score | 22 (18–26) |
| Baseline vasopressor use | 60 (52) |
| Admission category | |
| Medical | 78 (68) |
| Surgical | 24 (21) |
| Trauma | 6 (5) |
| Neurological/neurosurgical | 6 (5) |
| Burns | 1 (1) |
| Comorbidity | |
| Coronary artery disease | 23 (20) |
| Congestive heart failure | 16 (14) |
| Arrhythmia | 15 (13) |
| Peripheral vascular disease | 14 (12) |
| Diabetes mellitus | 40 (35) |
| Renal insufficiency | 13 (11) |
| Dialysis dependency | 4 (4) |
| Chronic obstructive pulmonary disease | 16 (14) |
| Liver disease | 8 (7) |
| Obesity | 16 (14) |
| Solid malignancy | 18 (16) |
| Leukemia/lymphoma | 1 (1) |
| Steroids/immunosuppression | 10 (9) |
| Infection characteristics | |
| Acquisition of bacteremia | |
| Community-acquired | 69 (60) |
| Hospital-acquired | 19 (17) |
| ICU-acquired | 27 (24) |
| Source of bacteremia | |
| Lung | 31 (27) |
| Intra-abdominal/hepato-biliary | 29 (25) |
| Urinary tract | 26 (23) |
| Vascular-catheter-related | 9 (8) |
| Skin and/or soft tissue | 4 (3) |
| Other | 4 (3) |
| Undefined/unknown | 12 (10) |
| Top 10 most commonly isolated pathogens in blood culturesb | |
| Escherichia coli | 28 (22) |
| Klebsiella spp. | 18 (14) |
| Enterococcus spp. | 17 (13) |
| Streptococcus pneumoniae | 13 (10) |
| Coagulase-negative staphylococci | 12 (9) |
| Enterobacter spp. | 6 (5) |
| Pseudomonas spp. | 4 (3) |
| Serratia spp. | 4 (3) |
| Citrobacter spp. | 3 (2) |
| Streptococcus anginosus group | 3 (2) |
aAll data are presented as medians and interquartile ranges (IQR) unless otherwise specified
bA total of 24 different bacterial species were isolated among the index blood cultures of the 115 patients; the denominator for these percentages is all organisms isolated from patients’ index blood cultures