Figure - PMC

Skip to main content

An official website of the United States government

Here's how you know

Here's how you know

Official websites use .gov
A .gov website belongs to an official government organization in the United States.

Secure .gov websites use HTTPS
A lock ( ) or https:// means you've safely connected to the .gov website. Share sensitive information only on official, secure websites.

View full-text article in PMC

. 2018 Feb 16;8:3167. doi: 10.1038/s41598-018-21548-x

Search in PMC
Search in PubMed
View in NLM Catalog
Add to search

© The Author(s) 2018

Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The images or other third party material in this article are included in the article’s Creative Commons license, unless indicated otherwise in a credit line to the material. If material is not included in the article’s Creative Commons license and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this license, visit http://creativecommons.org/licenses/by/4.0/.

PMC Copyright notice

(a) Rockman technique. (b to j) Schematic description of steps for the Double loop-clip technique. (c) B-mode echocardiographic image in modified right parasternal view of the thoracic aorta used to measure mid aortic arch luminal diameter, between the innominate trunk and the left carotid artery. This distance was obtained preoperatively and used to calculate the inter-knot span of the suture for the double loop-clip technique and customize the constriction to the mouse´s somatometry. (d) The suture was prepared prior to the operation with two knots spread apart a controlled distance (5 mm in the example) intended to define the degree of constriction. (e) The suture is looped twice around the mid-aortic arch (f), and (g) a vascular microclip applied under both knots which produces the preassigned level of stenosis as seen in the silicone cast of the thoracic aorta (h). (i) During the reoperation for releasing the constriction, pulling from the microclip allows its separation from the aortic wall, which facilitates severance of the suture avoiding the risk of aortic laceration. After release of the constriction the aorta recovers its flow section even though a mild stenosis remains (h). DLC: Double loop-clip.