TABLE II.

Comparison of statistics extracted from receiver operator characteristics for passive cavitation imaging (PCI) and plane wave B-Mode imaging grouped by peak negative pressure (all pulse durations), including the area under the receiver operator characteristic (AUROC), accuracy, sensitivity, specificity, positive predictive value (PPV), and negative predicative value (NPV). No compression of the passive cavitation image acoustic power or the plane wave B-mode grayscale value was used in the computation of these values. Bold values indicate a significant difference between plane wave B-mode and PCI.

Peak Negative Pressure	12 MPa		15 MPa		18 MPa		20 MPa		23 MPa
Statistic	B-Mode	PCI	B-Mode	PCI	B-Mode	PCI	B-Mode	PCI	B-Mode	PCI
AUROC	0.68 ± 0.05	0.85 ± 0.09	0.88 ± 0.07	0.96 ± 0.05	0.84 ± 0.10	0.97 ± 0.04	0.88 ± 0.07	0.95 ± 0.06	0.81 ± 0.06	0.96 ± 0.03
Accuracy	0.84 ± 0.06	0.88 ± 0.07	0.88 ± 0.07	0.91 ± 0.07	0.83 ± 0.05	0.92 ± 0.07	0.82 ± 0.05	0.89 ± 0.05	0.78 ± 0.04	0.90 ± 0.05
Sensitivity	0.30 ± 0.13	0.50 ± 0.22	0.51 ± 0.18	0.65 ± 0.20	0.56 ± 0.23	0.78 ± 0.13	0.53 ± 0.19	0.82 ± 0.13	0.49 ± 0.09	0.88 ± 0.11
Specificity	0.96 ± 0.04	0.96 ± 0.05	0.98 ± 0.04	0.97 ± 0.05	0.93 ± 0.06	0.97 ± 0.03	0.94 ± 0.06	0.92 ± 0.08	0.94 ± 0.08	0.90 ± 0.07
PPV	0.60 ± 0.16	0.71 ± 0.14	0.85 ± 0.20	0.87 ± 0.08	0.77 ± 0.08	0.92 ± 0.05	0.78 ± 0.01	0.80 ± 0.06	0.81 ± 0.04	0.83 ± 0.03
NPV	0.86 ± 0.04	0.90 ± 0.04	0.89 ± 0.04	0.92 ± 0.06	0.84 ± 0.04	0.92 ± 0.07	0.83 ± 0.06	0.93 ± 0.03	0.78 ± 0.05	0.94 ± 0.05