Table 1.

Study demographics at baseline.

Demographics at Baseline
	Non-Carriers	Asymptomatic Carriers	Symptomatic Carriers
Number	148	141	88
Females (%)	85 (57%)	78 (55%)	49 (56%)
Age (years/sd)	39·5 (11·4)	34·6 (9·2)	45·7 (9·9)
MMSE (mean/sd)	29·0 (2·7)	28·8 (2·7)	23·9 (10·2)
CDR-SOB (mean/SD)	0·0 (0·2)	0·0 (0·1)	3·6 (3·5)
EYO (years/sd)	−8·9 (11·4)	−13·7 (9·2)	0·5 (7·1)
PSEN1/PSEN2/APP	122/17/9 (82/11/6%)	117/16/8 (83/11/6%)	76/6/6 (86/7/7%)
N with Follow up (%)	70 (47%)	73 (52%)	58 (66%)
N of visits*(sd)	2·3 (0·8)	2·3 (0·8)	2·8 (1·2)
Follow up in years* (sd)	3·0 (1·7)	3·0 (1·6)	2·0 (1·3)
Summary of Imaging Data
Data By Modality	PIB	FDG	MRI
1 visit	184	177	176
2 visits	124	131	145
3 visits	23	27	35
4 visits	10	11	11
5 visits	4	5	8
6 visits	1	1	2
Total Subjects	346	352	377

^*Summary values are only for those individuals with longitudinal data

EYO - estimated years to dementia onset

MMSE – Mini Mental State Examination

CDR-SOB – Clinical Dementia Rating Sum of Boxes