Table 2.

A psychophysiological interaction (PPI) analysis revealed differences in pain-induced connectivity from the periaqueductal gray in migraineurs and controls.

			COG MNI coordinates
Brain region	Laterality	Z-Stat	X	Y	Z	Vol (voxels)
HC > migraine
Temporal pole sup	L	2.73	−46	20	−20	704
Precuneus	L	2.56	−12	−68	52	482
Front Sup Medial	R	2.38	6	50	40	478
Cerebellum IX	L	2.5	−20	−46	−50	450
Cerebellum Crus 1	L	2.47	−18	−78	−28	422
Mid. Occipital	R	2.89	30	−90	18	267
Cerebellum Crus 1	R	2.45	30	−86	−24	207
Mid. Occipital	L	2.51	−30	−98	−4	179
Migraine > HC
Calcarine	R	2.74	10	−78	14	2,977
Postcentral	L	2.43	−60	−14	28	2,010
SMA	R	2.62	12	−16	70	1,424
Insula	R	2.39	42	−6	10	405
Precentral	R	1.96	42	−10	50	373
Sup. occipital	L	2.27	−20	−84	44	368
Middle temporal	R	2.25	52	−58	8	353
Inf. orbital	L	2.15	−38	34	−12	192
Precentral	L	2.26	−24	−24	72	187
Fusiform gyrus	L	2.12	−32	−24	−30	165
Parahippicampal area	R	2.19	28	−12	−26	155
Thalamus	L	2.53	−10	−12	−2	131
Angular gyrus	L	2.48	−48	−74	32	123
Cuneus	L	1.72	−10	−72	28	120
Thalamus	R	2.14	10	−20	4	93
Medial orbital	R	1.71	4	62	−14	84
Postcentral	L	2.44	−22	−36	58	79
Pyramis	L	2.04	−46	−78	−44	44
Fusiform gyrus	R	1.81	28	−72	−8	21

COG, center of gravity; MNI, Montreal Neurological Institute coordinates; SMA, supplementary motor area; Vol, volume.