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. 2018 Feb 13;9:61. doi: 10.3389/fneur.2018.00061

Table 3.

A correlation analysis revealed a correlation between monthly frequencies of attacks with periaqueductal gray connectivity strength during painful stimulation.

COG MNI coordinates
Brain region Side Z-stat X Y Z Vol (voxels)

Frequently correlation
Positive correlation
WM (cluster including orbitofrontal cortex and caudate) L 2.62 −24 34 −6 2,894
Sup. occipital R 2.58 24 −70 30 2,258
SMA R 2.83 4 −18 70 1,847
Cerebellum 9 R 2.56 8 −48 −58 941
Inf. frontal R 2.43 36 18 34 861
Precentral/postcentral (face area) L 2.27 −56 −8 32 683
Cerebellum crus 1 R 2.42 46 −62 −40 578
Inf. Temporal gyrus R 1.97 52 0 −40 284

Negative correlation
Putamen L 2.5 −22 4 6 871
Sup. frontal R 2.58 20 48 40 334
Sup. parietal R 2.33 26 −62 60 273
Precuneus L 2.07 −8 −68 58 221
Cerebellum VI R 2.09 18 −68 −28 178
Cerebellum VIII R 2.1 28 −42 −52 159
Sup. temporal lobe L 2.42 −48 −20 12 154
SMA R 2.51 4 8 68 150
Mid. occipital R 2.12 32 −94 2 146
Mid. cingulum L 2.23 45 77 52 141
Precentral L 2.2 −26 −14 56 118
Sup. occipital R 2.55 28 −92 22 107
Cerebellum 9 L 2.28 −22 −42 −48 99
Precentral L 2.38 −38 2 60 83
Inf. frontal tri L 2.07 −54 32 14 80
Mid. frontal L 2.5 −40 44 30 76
Cerebellum IV/V R 2.17 18 −52 −20 71
Paracentral lobule L 1.85 −14 −36 74 60
Precentral R 2.1 30 −26 72 60
Insula L 2.15 −38 −4 16 60
SMA L 2.02 2 4 40 58
Cerebellum VIII L 1.73 −44 −48 −50 55
Cerebellum crus 2 L 2.08 −26 −78 −46 54
Temporal pole L 2.24 70 74 29 52
Precentral L 1.99 −32 −30 40 51
ACC R 2.37 4 34 10 50
Vermis 4/5 1.99 2 −50 -22 47
Caudate R 2.2 6 12 6 41
SMA L 2.2 −2 12 48 34
Mid. frontal R 2.18 30 30 28 34
Precentral R 1.94 48 6 28 30
Sup. frontal L 2.36 −26 46 40 29
Lingual gyrus R 2.06 18 −100 −8 28

ACC, anterior cingulate cortex; COG, center of gravity; Inf, inferior; Mid, middle; MNI, Montreal Neurological Institute coordinates; SMA, supplementary motor area; Sup, superior; Vol, volume; WM, white matter.