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. 2018 Jan 24;37(3):475–483. doi: 10.1007/s10096-018-3193-y

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© The Author(s) 2018

Open Access This article is distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made.

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Fig. 2 — Principal response curve (PRC) and redundancy analysis (RDA) of the faecal microbiota in control, short-term (ST) and long-term (LT) infants. a PRC analysis. Genera with a score lower than − 0.5 or higher than 0.5 are shown on PRC1 (Bifidobacterium: 4.58; Enterococcus: − 1.83; Clostridium: − 1.70; Enterobacter: − 0.73). b Relative abundance of the bacterial genera associated with temporal development as observed in the PRC. Per time point, the average relative abundance is shown. c RDA showing the main bacterial genera explaining the variation. Percentages indicate the fit of the bacterial genera into the ordination space. Genera with a fit over 20% are shown. d RDA showing the clinical factors associated with microbiota composition. Clinical factors that significantly (p < 0.05) explain the variation are shown. AB: antibiotics; PREE: pre-eclampsia