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. 2018 Feb 13;12:15. doi: 10.3389/fncir.2018.00015

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Copyright © 2018 Han, Zhang, Zhu, Chen and Li.

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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Automatic DNMS training protocol and behavioral results. (A) Design paradigm and time line for the DNMS training. Both non-matched and matched trials were applied. (B) Performance of mice in the DNMS training phase. Bin size: 24 trials. (C–E) Correct rejection (CR) rate, hit rate and d’ in the DNMS training, respectively. (F) Re-learning in each day of the DNMS training, measured by the number of trials to criterion (defined as more than 80% performance in 24 consecutive trials). NRC, not reaching criteria. Mice that were NRC in the 2nd and 3rd days were not included. (G) Licking rates for training day 1 and 5. (H) Licking efficiency in the DNMS training. Licking efficiency was defined as the ratio of successful licks resulting water reward.