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. 2018 Jan 2;2018:2870503. doi: 10.1155/2018/2870503

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Copyright © 2018 Jui-Shu Chang et al.

This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

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The effect of AVA on NO (a), TNF-α (b), IL-1β (c), IL-6 (d), and IL-10 (f) expression in mice with ALI. Mice were given AVA (125, 250, and 500 mg/kg) via intraperitoneal injection 1 h before challenge with LPS. The BALF was collected 6 h following LPS challenge to analyze the inflammatory cytokines NO, TNF-α, IL-1β, IL-6, and IL-10. Each value represents the mean ± SD. ^### p < 0.001 compared with the control group. ^∗ p < 0.05, ^∗∗ p < 0.01, and ^∗∗∗ p < 0.001 compared with the LPS group (one-way ANOVA followed by Scheffe's multiple range test).