Table 3.

Mean ± SD of histological alterations (ISI) in liver (score per field) and ileum (score per villi) at 7 and 21 days of age.

	Liver		Ileum
	7 days	21 days	7 days	21 days
Challenge
Control	23.49 ± 6.53a	12.26 ± 5.78b	5.29 ± 4.39	9.99 ± 4.55
SH	20.25 ± 7.13b	20.63 ± 6.61a	4.56 ± 4.54	10.42 ± 3.54
Probiotic
Control	24.09 ± 5.49a	16.84 ± 6.74b	4.36 ± 4.32b	9.11 ± 4.16b
250	20.82 ± 7.63b	17.48 ± 7.41b	4.42 ± 4.24b	11.52 ± 3.95a
500	19.08 ± 7.09b	19.19 ± 7.06a	5.71 ± 4.84a	10.21 ± 3.20b
Interaction
Control	23.70 ± 5.82a	9.93 ± 5.25c	5.01 ± 0.57	10.50 ± 5.22a,b
PRO 250	23.10 ± 7.27a	11.40 ± 5.28c	4.11 ± 0.57	10.47 ± 4.94a,b
PRO 500	23.67 ± 6.52a	15.45 ± 5.42b	6.75 ± 0.57	9.00 ± 3.13b,c
SH Control	24.28 ± 5.34a	20.31 ± 6.39a	4.03 ± 0.40	8.42 ± 3.33c
SH + PRO 250	19.67 ± 7.58b	20.52 ± 6.38a	4.57 ± 0.40	12.04 ± 3.24a
SH + PRO 500	16.79 ± 6.23c	21.06 ± 7.06a	5.13 ± 0.42	10.79 ± 3.08a
Probabilities
Challenge (P1)	<0.001	<0.001	0.081	0.204
Probiotic (P2)	<0.001	<0.001	0.002	<0.001
Interaction (P1 × P2)	<0.001	<0.001	0.106	<0.001

^a,b,cDifferent letters in the same column indicate significant differences at P < 0.05 at Kruskal–Wallis test.

Bold values were used to distinguish statistical differences.