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. 2018 Feb 6;9:61. doi: 10.3389/fphar.2018.00061

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Copyright © 2018 Xiong, Cui, Yu, Wang and Song.

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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Cellular uptake and intracellular locations of PEG-CD/AD nanoparticles in HepG2 cells. (A) Flow cytometry analysis of the cells with the treatments of PEG-CD/AD nanoparticles for different time. (B) Confocal images of the cells. (C) Schematic illustration of cell internalization of PEG-CD/AD nanoparticles and intracellular release of DOX.