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. Author manuscript; available in PMC: 2019 Feb 2.
Published in final edited form as: Prog Neuropsychopharmacol Biol Psychiatry. 2017 Oct 28;81:114–121. doi: 10.1016/j.pnpbp.2017.10.019

Table 2.

Mean and Standard Deviation (in parentheses) for Right and Left Superior Longitudinal Fasciculus Metrics and Asymmetry Indices.

Metric Right Superior Longitudinal Fasciculus Left Superior Longitudinal Fasciculus Asymmetry Index
Controls
(N=23)
Patients
(N=27)
p-value Controls
(N=23)
Patients
(N=27)
p-value Controls
(N=23)
Patients
(N=27)
p-value
Number of Crossing Fibers 1.87 (0.09) 1.87 (0.15) NS 1.82 (0.10) 1.90 (0.14) .04 1.19 (2.36) −.64 (2.30) .008
MDA .476 (0.02) .475 (0.01) NS .490 (0.02) .479 (0.01) 01 −1.43 (1.64) −.34 (1.54) .019
GFA .179 (.007) .180 (.006) NS .185 (.008) .179 (.006) .006 −1.51 (1.84) .08 (1.94) .005
FA .463 (0.03) .462 (0.02) NS .472 (0.03) .453 (0.02) .004 −1.05 (2.15) .96 (2.17) .002
Volume (cc) 12.7 (4.5) 11.4 (3.0) NS 12.3 (3.9) 11.9 (2.9) NS 1.20 (10.2) −2.28 (11.1) NS

Notes. Number of crossing fibers = number of ODF peaks found for each voxel; MDA (multi directional anisotropy) = anisotropy calculated from ODFs by using ratio of peaks to troughs in the ODFs and identical to FA for single-directional Gaussian diffusion with values ranging from 0 to 1; GFA (generalized fractional anisotropy) defined according to Tuch (2004); and FA (fractional anisotropy) = anisotropy calculated based on a DTI model with values ranging from 0 to 1; Volume = volume based on traversed locations for tract. The asymmetry index was computed using the following formula = [(R−L)/(R+L)] * 100.