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. Author manuscript; available in PMC: 2019 Mar 1.
Published in final edited form as: Nucl Med Biol. 2017 Dec 24;58:67–73. doi: 10.1016/j.nucmedbio.2017.12.004

Figure 2.

Figure 2

Biodistribution analyses in mice with PDAC xenograft tumors. (A) Biodistribution at 24 h after i.v. injection of 212Pb-376.96 or 212Pb-F3-C25 (0.74 MBq) in groups of athymic nude mice (n = 4/group) bearing s.c. PDX Panc039 tumors. (B) Biodistribution at 24 h after i.v. co-injection of 99mTc-376.96 (6.02 MBq) and 125I-F3-C25 (22.39 kBq) in athymic nude mice (n = 5 mice) bearing orthotopic PDAC3 tumors; 125I was counted after 99mTc had fully decayed. After euthanization of mice, tissues were collected, weighed, and counted to determine the percent of the injected dose per gram (% ID/g) of tissue. Data are presented as mean ± standard deviation. *p<0.05; ***p<0.001