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. Author manuscript; available in PMC: 2019 Feb 15.
Published in final edited form as: Bioorg Med Chem Lett. 2018 Jan 24;28(4):658–663. doi: 10.1016/j.bmcl.2018.01.025

Fig. 3.

Fig. 3

Effects of (−)-epicatechin (Epi) and Epi derivatives on eNOS/NO pathway activation. (A) Epi derivatives induced nitric oxide (NO) production and (B) endothelial nitric oxide synthase (eNOS) activation (phosphorylation at Ser-1179 [p-eNOS]) in bovine coronary artery endothelial cells (BCAEC). All compounds were tested at 1 μM. Control was arbritarily set to 1 and values are reported as mean ± SEM, p<0.05 * vs control or ^ vs Epi (n=5 per group).