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. Author manuscript; available in PMC: 2019 Feb 1.
Published in final edited form as: Am J Geriatr Psychiatry. 2017 Oct 10;26(2):134–147. doi: 10.1016/j.jagp.2017.09.027

Table 2.

ChEI Discontinuation Guidelines in Textbooks

No
Recommendation
Recommend
to Not
Discontinue
Discontinue Based On:
Lack of
Response/
Loss of
Effective
ness
Side Effects
/ Adverse
Events
Severity of
Cognitive
Impairment
Functional
Level /
Stage
Institutionali
-zation
Behavio
r
Medica
l Status
Family/ CG/
Patient
Preference
Neurology
(46) X
(47) X
(48) X
(49) X
(36) X
(50, 51) X
Geriatrics
(52) X
(53) X
(54) X
(55) X X X
(56) X
Psychiatry
(57) X
(37) X
(58) X X
(59) X
(60) X
Geriatric Psychiatry/Neuropsychiatry
(61) X
(62) X
(63) X
(41) X
(64) X
Clinical Pharmacology
(65) X
(66) X
(42) X X
(67) X
(68) X
Family Medicine/Internal Medicine
(69) X
(70) X
(71) X
(40) X
(72) X X
Dementia
(38) X
(39) X X X
(73) X
(74) X
(75) X

CG = caregiver