Table 5.

DEGs in dendritic cells (DCs) from patients with type 1 diabetes (T1D) after PSA-liposomes and PSB-liposomes phagocytosis.

Category	Number of DEGs	P value	Representative downregulated genes	Representative upregulated genes
Adhesion	3	≤0.001076	SCYL3, MEGF9	IGSF9
Antigen processing and presentation	7	≤0.001024	KBTBD6, BTK, CDC23, UBE2E3, CD1D, CUL3, KIF11
Apoptosis	6	≤0.000593	BLCAP, PMP22, LMNB1, CASP3, DCAF7, BCL2L1
Cell cycle	9	≤0.001162	CSRP2BP, BUB1, MCPH1, CDK13, PCNA, MCM4, SMC2, NCAPG2, AURKA
Cytokine signaling	9	≤0.001191	TRIM5, SOCS2, STX3, TNFRSF11A, NUP160	TNFSF14, VEGFA, TNF, IFNLR1
Cytoskeleton organization	6	≤0.000897	MAPRE2, RMDN1, CKAP2, MDM1, RCSD1, CDC42SE1
DNA replication and repair	8	≤0.000995	WRNIP1, PAXIP1, MSH2, RAD51C, DCLRE1A, ALKBH1, PARG, MLH1
Gene expression	36	≤0.001293	ZNF436, MYB, ZFP36L2, MIER3, ZBTB5, HHEX, GTF2B, DYRK2, NFIA, ZBTB39
Immunoregulation	25	≤0.001146	GIMAP4, SLAMF6, DAPP1, MEF2C, BST1, PROS1, MNDA	TNFAIP3, PLAUR, NFKBIA
Metabolism	43	≤0.001225	C9orf64, HPGD, TIMMDC1, ICK, DDO, DCTD, CDYL2, GLRX, TPK1	MFSD2A
Molecule transport	14	≤0.001252	ERLIN1, SLC10A7, UNC50, ATP10D, SLC40A1, CLCN3, STIM2	SLC43A3, SLCO4A1, CLCN6
Post-translational protein modification	13	≤0.001056	FBXO36, NSMCE4A, VWA5A, FBXO25, DCAF12, CBX4, RMND5A, LNX2, BTBD3	PPME1
Signal transduction	18	≤0.001298	SNN, SKI, PAQR8, UBFD1, N4BP1, FZD5, NET1, ZBED3, FRAT2	SHB
Vesicle-mediated processes	8	≤0.001208	GOLPH3L, SEC22C, RAB32, EHBP1, KIF20B, SNX18	CYTH4, LDLR

DEGs, differentially expressed genes.