Table 2.

Mean ± SEM immobility (sec) data from Day 1 for female and male California mice.

Time point	Control vehicle	Control norBNI	Control U50,488	Stress vehicle	Stress norBNI	Stress U50,488
Female California mice
First 5 min (Bin 1)	31.8 ± 6.5	36.6 ± 8.7	27.6 ± 8.7	21.4 ± 11.2	22.5 ± 10.7	21.0 ± 8.3
Second 5 min (Bin 2)	48.6 ± 11.2	53.5 ± 8.1	41.7 ± 9.1	55.17 ± 13.3	35.5 ± 38.6	56.6 ± 13.6
Third 5 min (Bin 3)	63.9 ± 15.2	66.9 ± 13.1	46.0 ± 8.7	66.7 ± 16.9	34.5 ± 9.9	51.6 ± 19.1
Time point	Vehicle	norBNI
Male California mice
First 5 min (Bin 1)	27.9 ± 5.4	28.5 ± 6.5
Second 5 min (Bin 2)	57.1 ± 8.1	40.3 ± 8.2
Third 5 min (Bin 3)	73.0 ± 11.8	42.5 ± 6.9∗

Immobility scores analyzed with two-way ANOVA (stress and drug treatment). ^∗p < 0.05 vs. corresponding vehicle.