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. 2018 Feb 14;11:39. doi: 10.3389/fnmol.2018.00039

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Copyright © 2018 Madrid, Chopra and Alisch.

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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Differentially methylated and hydroxymethylated genes have neuronal functions. (A) Top ten gene ontological terms associated with all differentially methylated genes (B) Top ten gene ontological terms associated with all differentially hydroxymethylated genes (C) Venn diagram of the overlap of DML-associated genes (blue; N = 3,365), DhML-associated genes (red; N = 2,875) with genes known to function in intelligence, cognition, and learning and memory similarly tested within the gene universes (yellow; N = 5,137). The significant overlaps are indicated by an asterisk (Chi-square P < 0.05).