Skip to main content
. 2018 Feb 14;9:205. doi: 10.3389/fmicb.2018.00205

Figure 2.

Figure 2

Inhibition index of CF efflux (Δ) by ABCC modulators in epimastigote forms of the T. cruzi Y strain. Inhibition index of CF efflux (Δ) was calculated by the ratio between the CF MFI of the parasite in the presence of the modulator and the CF MFI in the absence of the modulator (CTL). Graphs in (A,B) represent the Δ values in the presence of the modulators at 27 and 37°C, respectively. Comparison between Δ indexes at 27 and 37°C are shown in (C) for 7.5 mM probenecid, in (D) for 600 μM indomethacin and in (E) for 200 μM MK-571. The Kruskal–Wallis and (C–E) Mann–Whitney (A,B) statistical tests were performed with n = 10 (27°C) and n = 8 (37°C) independent experiments. Bars represent the mean ± standard error and the significance values were represented by *p < 0.05, **p < 0.01, and ***p < 0.001.