Figure 3.
The NPs modified with CTCE9908 peptides enhanced coumarin 6 tissue uptake in the fibrotic livers of CCl4-treated mice. A, The tissue distribution of coumarin 6 in different formulations (n=7-8). Coumarin 6-loaded CTCE9908-NPs showed enhanced tissue uptake in the fibrotic livers 4 h after I.V. administration. B, Representative confocal images of the uptake of coumarin 6 in different formulations by the fibrotic livers. Green, coumarin 6-loaded NPs; blue, DAPI. Scale bar=100 μm. The data are given as the mean values ± S.E.M., *p<0.05 and ***p<0.001.