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(a) Tumor volume before treatment and 12 days after treatment (bladders were exposed to 660 nm laser for 15 min (200 mW/cm2)), (*p<0.05). (b) Photodynamic effect of HSA-MnO2-Ce6 NPs on bladder cancer was detected pre-treatment and on day 3 by CEUS and US. (c) Representative images of orthotopic bladder cancers before and after treatments and corresponding HE-stained bladder sections. Error bars indicate standard deviations of four independent measurements.
