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. 2018 Jan 1;8(4):1121–1130. doi: 10.7150/thno.22601

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⁶⁸Ga-BBN-RGD PET/CT in primary tumors with different histological subtypes of breast cancer. (A) A patient of 56y with invasive ductal carcinoma (A1-A3, arrow), estrogen receptor (ER) positive, progesterone receptor (PR) positive, human epidermal growth factor receptor- 2 (HER-2) positive. The lesion had a SUVmax of 7.5 with strong GRPR expression (A4) and weak integrin αvβ3 expression (A5). (B) A patient of 53y with invasive ductal carcinoma (B1-B3, arrow), ER negative, PR negative, HER-2 positive. The lesion had a SUVmax of 2.1 with week GRPR expression (B4) and weak integrin αvβ3 expression (B5). (C) A patient of 43y with triple negative breast cancer (TNBC) (C1-C3, arrows). The lesions had a SUVmax of 3.4 with moderate GRPR expression (C4) and weak integrin αvβ3 expression (C5).