Figure 3.

Effect of CIHH on perivascular inflammation and pro-inflammatory cytokines expression in MCT-treated rats. Peri-vascular inflammation score was increased by MCT injection and the effect of MCT was prevented by CIHH treatment (A). TNF-α (B) and IL-6 (C) levels in serum of the rats treated with MCT and CIHH. Immunohistochemical staining of pulmonary TNF-α (D) and IL-6 (E) protein expression in experimental rats (magnification ×200). MCT induced an increase of TNF-α and the IL-6 level was significantly antagonized by CIHH. Values are means±SD, n=10 for each group. **P<0.01, compared to MCT group; ^#P<0.05, ^##P<0.01, compared to control group