Table 1.
Effects of Scutellarin (Scu) on troponin T (CTn-T), troponin I (CTn-I), lactate dehydrogenase (LDH) and aspartate aminotransferase (AST) in rat serum with isoprenaline (ISO)-induced cardiotoxicity (n=6)
| Groups | CTn-I(pg/mL)a | CTn-T(ng/mL)a | LDH(IU/L)a | AST(U/L)a |
|---|---|---|---|---|
| G1(saline) | 194.16±39.63c | 267.39±17.68c | 5.52±0.62c | 43.23±2.85c |
| G2(isoprenaline) | 298.96±48.05b | 405.56±54.30b | 8.22±1.43b | 64.28±2.39b |
| G3(ISO+10mg/gS. miltiorrhiza) | 171.55±50.78c | 317.56±27.11c | 6.39±1.47 | 53.41±7.47bc |
| G4(ISO+10mg/kgScu) | 195.83±20.92c | 330.91±27.48bc | 6.60±1.23 | 47.89±10.57c |
| G5(ISO+20mg/kgScu) | 175.48±64.88c | 324.37±36.75bc | 6.14±1.30c | 46.40±1.43c |
| G6(ISO+40mg/kg Scu) | 167.36±28.42c | 280.95±29.70c | 5.13±0.71c | 46.32±3.81c |
a
Values represent mean±SD of six animals;
b
Significantly different from saline group (G1) P<0.01;
c
Significantly different from ISO group (G2) P<0.01