Figure 4.
Vascular endothelial growth factor (VEGF) was confirmed to be the target gene of miR-103 by luciferase reporter gene assay. A, Putative miR-103 binding sites in the coding sequence region of VEGF 3’UTR; B, Luciferase activity analysis after con-transfection of VEGF 3’UTR-WT/-MUT plasmids with miR-103 mimic or miR-103 NC; *, P< 0.05 compared with NC group