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. 2017 Sep 5;163(9):1283–1291. doi: 10.1099/mic.0.000510

Table 3. Influence of the potential inhibitors on mevalonate kinase activity.

nd, not determined. Results of single experiments are represented. Relative catalytic activity (%) of the enzymes is indicated. Activity without potential inhibitors was taken as 100 %.

MVK DPM DMAPP GPP FPP Reference
1 mM 5 mM 5 µM 10 µM 100 µM 5 µM 10 µM 100 µM
sce 96 8 nd nd 9 nd nd 10 This work
mma 85 91 nd nd 96 nd nd 98 This work
mcl 99 122 nd nd 104 nd nd 105 This work
mpd 105 97 nd nd 101 nd nd 101 This work
nmr 97 95 nd nd 100 nd nd 92 This work
mja nd nd 58 45 nd 46 35 nd [11]