Table 2. Univariate and multivariate analysis of factors associated with ESBL-E carriage.
Univariate OR (95 % CI) |
P-value | Adjusted multivariate OR (95 % CI) | Final adjusted multivariate OR (95 % CI) | |
---|---|---|---|---|
Demographics | ||||
Gender | ||||
Male | 1 | 1 | – | |
Female | 1.33 (0.56–3.16) | 0.516 | 1.31 (0.51–3.36) | |
Age (years) | ||||
6–11 | 1 | 1 | ||
12–16 | 1.36 (0.57–3.27) | 0.493 | 1.15 (0.44–2.96) | – |
Median age (IQR) years | 0.291 | |||
Current CD4 count (cells µl−1) | ||||
<350 | 1.81 (0.55–6.01) | 0.330 | 1.08 (0.21–5.49) | – |
≥350 | 1 | |||
Median CD4 count (IQR) | 0.548 | |||
Current viral load (copies ml−1) | ||||
≤50 | 1 | 1 | ||
>50 | 1.03 (0.41–2.57) | 0.948 | 0.93 (0.29–3.00) | – |
Missing | – | |||
Duration on ART (years) | ||||
≤1 | 7.68 (2.03–29.0) | 0.003 | 8.19 (2.06–32.48) | 8.47 (2.22–2.27) |
>1 | 1 | 1 | 1 | |
Median duration on ART (IQR) years | 0.145 | |||
Clinical characteristics | ||||
Admitted to the hospital in last 12 months | ||||
No | 1 | |||
Yes | 1.87 (0.36–95.6) | 0.453 | – | – |
Admitted to the hospital for a chest infection/pneumonia in last 12 months | ||||
No | 1 | 1 | ||
Yes | 6.77 (0.907–50.587) | 0.062 | 8.12 (0.98–67.17) | 8.47 (1.12–64.07) |