Table 1.
Serial Number | Name of protein | Role in crystallization | |||
---|---|---|---|---|---|
Nucleation | Growth | Aggregation | Cell adherence | ||
1 | Nephrocalcin (NC) | I | I | I | — |
2 | Tamm–Horsfall protein (THP) | P | — | I/P | — |
3 | Osteopontin/uropontin (OPN) | I | I | I | I/P |
4 | Albumin | P | — | I | — |
5 | Urinary prothrombin fragment-1 (UPTF1) | I | I | I | — |
6 | Alpha-1-microglobulin | — | — | I | — |
7 | S100A | — | I | I | — |
8 | Inter-alpha-inhibitor | I | I | I | I |
9 | Bikunin | I | I | I | I |
10 | Renal lithostathine | — | I | — | — |
11 | Alpha defensin | — | P | P | — |
12 | Human phosphatecytidylyl transferase 1, choline, beta | — | I | — | — |
13 | Myeloperoxidase | — | P | P | — |
14 | Nucleolin | — | — | — | P |
15 | Histone-lysine N methyltransferase | — | I | I | — |
16 | Inward rectifier K channel | — | I | I | — |
17 | Protein Wnt-2 | — | I | I | — |
18 | Alpha-2HS glycoprotein | P | I | — | — |
19 | Crystal adhesion inhibitor (CAI) | — | — | — | I |
20 | Hyaluronic acid (HA) | — | — | — | P |
21 | Chondroitin sulphate | — | I | I | — |
22 | Heparin sulphate (HS) | — | I | — | — |
23 | Human urinary trefoil factor 1(THF1) | — | I | — | — |
24 | Monocyte chemoattractant protein-1 (MCP 1) | — | — | — | P |
25 | Annexin II | — | — | — | P |
26 | CD44 | — | — | — | P |
27 | Matrix Gla protein (MGP) | — | I | — | I |
28 | Histone H1B | — | P | — | — |
29 | Fibronectin | — | — | I | I |
30 | Collagen | P | — | — | — |
31 | Glycosaminoglycans | I | I | I | I |
32 | Citrate | — | I | — | — |
33 | Pyrophosphate | — | I | — | — |
34 | Magnesium | — | I | — | — |
I: inhibitor; P: promoter; “—”: no effect.