Table 1. Demographic summary of ABCB1 (rs1045642) and SLCO1B1 (rs4149056) genotyped population.
| ABCB1 (rs1045642) |
N=458 | SLCO1B1 (rs4149056) |
|||||
|---|---|---|---|---|---|---|---|
| CC (n=206) | CT (n=193) | TT (n=59) | TT (n=384) | CT (n=71) | CC (n=3) | ||
| Sex, n (%) | |||||||
| Male | 167 (81.1) | 150 (77.7) | 48 (81.4) | 365 (79.7) | 311 (81.0) | 53 (74.6) | 1 (33.3) |
| Female | 39 (18.9) | 43 (22.3) | 11 (18.6) | 93 (20.3) | 73 (19.0) | 18 (25.4) | 2 (66.7) |
| Race, n (%) | |||||||
| American Indian/Alaskan | 0 (0.0) | 2 (1.0) | 0 (0.0) | 2 (0.4) | 1 (0.3) | 1 (1.4) | 0 (0.0) |
| Asian | 1 (0.5) | 6 (3.1) | 3 (5.1) | 10 (2.2) | 9 (2.3) | 1 (1.4) | 0 (0.0) |
| Black or African American | 150 (72.8) | 91 (47.2) | 9 (15.3) | 250 (54.6) | 226 (58.9) | 24 (33.8) | 0 (0.0) |
| White | 43 (20.9) | 89 (46.1) | 45 (76.3) | 177 (38.6) | 134 (34.9) | 40 (56.3) | 3 (100.0) |
| Other | 12 (5.8) | 5 (2.6) | 2 (3.4) | 19 (4.1) | 14 (3.6) | 5 (7.0) | 0 (0.0) |
| Ethnicity, n (%) | |||||||
| Hispanic/Latino | 38 (18.4) | 51 (26.4) | 16 (27.1) | 105 (22.9) | 84 (21.9) | 20 (28.2) | 1 (33.3) |
| Not Hispanic/Latino | 168 (81.6) | 142 (73.6) | 43 (72.9) | 353 (77.1) | 300 (78.1) | 51 (71.8) | 2 (66.7) |
| Age (years) | |||||||
| Mean±s.d. | 32.1±7.4 | 30.2±6.9 | 30.9±8.5 | 31.1±7.4 | 31.4±7.4 | 29.6±6.9 | 29.3±12.1 |
| Weight (kg) | |||||||
| Mean±s.d. | 81.5±12.1 | 79.0±12.1 | 76.6±12.0 | 79.8±12.2 | 80.1±12.1 | 78.8±12.3 | 64.0±4.0 |
| BMI (kg m−2) | |||||||
| Mean±s.d. | 26.6±3.1 | 25.9±3.0 | 25.2±3.0 | 26.1±3.1 | 26.1±3.0 | 26.2±3.2 | 24.9±3.9 |
| CLcr (ml min−1) | |||||||
| Mean±s.d. | 134.0±26.7 | 137.0±25.2 | 138.0±25.3 | 136.0±25.9 | 134.5±26.3 | 141.0±22.7 | 146.7±25.2 |
Abbreviations: BMI, body mass index; CLcr, creatinine clearance; SD, standard deviation.