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. 2017 Apr 12;153(9):935–937. doi: 10.1001/jamadermatol.2017.0297

Table. Cross-sectional Associations of Sex Hormones With Hair Loss and Norwood-Hamilton Scale in Mena.

Regression Model Total Testosterone Androstenedione Free Testosterone DHEAS E2:TT Ratio
Hair Loss, Relative Risk (95% CI)
Age-adjusted 0.73 (0.97-1.04) 0.97 (0.94-1.00) 0.98 (0.94-1.02) 0.99 (0.95-1.03) 0.97 (0.94-1.01)
MV-adjustedb 0.77 (0.96-1.04) 0.96 (0.93-1.00) 0.98 (0.94-1.01) 0.98 (0.94-1.03) 0.97 (0.93-1.01)
Norwood-Hamilton Scale, Odds Ratio (95% CI)
Age-adjusted 1.14 (0.88-1.46) 0.92 (0.70-1.20) 1.12 (0.84-1.48) 0.76 (0.55-1.05) 1.02 (0.79-1.32)
MV-adjustedb 1.24 (0.93-1.65) 0.94 (0.71-1.23) 1.13 (0.84-1.53) 0.74 (0.53-1.03) 0.96 (0.72-1.30)

Abbreviations: DHEAS, dehydroepiandrosterone sulfate; E2, estradiol; MV, multivariable; TT, total testosterone.

a

The present data show the relative risk for the binary outcome hair loss and the odds ratios for the continuous outcome Norwood-Hamilton scale per standard deviation increase including 95% CIs. No significant associations were observed.

b

The multivariable model was adjusted for age, waist circumference, smoking status (3 categories), alcohol consumption, diabetes mellitus, and hypertension.