Table 2. Major Intraobserver Discrepancies and Agreement With GTC.

Case No./Group	WSI Diagnosis	TM Diagnosis	GTC Diagnosis
1/Melanocytic	In situ malignant melanoma	Invasive malignant melanoma	Invasive malignant melanoma
2/Melanocytic	In situ malignant melanoma	Invasive malignant melanoma	In situ malignant melanoma
3/Melanocytic	Invasive malignant melanoma	Atypical lentiginous compound nevus; severe atypia	Atypical lentiginous junctional nevus; severe atypia
4/Melanocytic	Lentiginous junctional nevus	Atypical lentiginous junctional nevus; moderate atypiaa	Atypical lentiginous junctional nevus; moderate atypia
5/Melanocytic	Lentigo/early junctional nevus	Atypical lentiginous junctional nevus; moderate atypiaa	Lentiginous junctional nevus
6/Melanocytic	Lentiginous compound nevus	Atypical lentiginous compound nevus; mild atypiaa	Atypical lentiginous compound nevus; moderate atypia
7/Inflammatory	Spongiotic dermatitis	Solar lentigo-seborrheic keratosis overlap	Spongiotic dermatitis
8/Inflammatory	Spongiotic dermatitis	Granuloma annulare	Spongiotic dermatitis
9/Nonmelanocytic	Verrucous keratosis	Actinic keratosis; hypertrophic variant	Verruca vulgaris
10/Nonmelanocytic	Verrucous benign keratosis	Bowenoid actinic keratosis	Actinic keratosis
11/Nonmelanocytic	Verruca vulgaris	Actinic keratosis; hypertrophic variant	Verruca vulgaris
12/Nonmelanocytic	Verruca vulgaris	Actinic keratosis; hypertrophic variant	Verruca vulgaris
13/Nonmelanocytic	Actinic keratosis	Solar lentigo	Actinic keratosis
14/Nonmelanocytic	Actinic keratosis	Spongiotic/Psoriasiform dermatitis	Actinic keratosis

Abbreviations: GTC, ground truth consensus; TM, traditional microscopy; WSI, whole-slide images.

^aModerate/mild atypia with the margins involved resulting in probable reexcision.