Table 1. Patient and Tumor Characteristics.
| Variable | MMS (n = 277) |
WLE (n = 385) |
P Value |
|---|---|---|---|
| Age, mean (SD), y | 64.0 (13.1) | 58.5 (15.6) | <.001 |
| Sex, No. (%) | |||
| Male | 172 (62.1) | 211 (54.8) | .06 |
| Female | 105 (37.9) | 174 (45.2) | |
| Race, No. (%) | |||
| White | 252 (91.0) | 354 (91.9) | .66 |
| Other/unknown | 25 (9.0) | 31 (8.1) | |
| Year of diagnosis | |||
| Mean (SD) | 2007 (3.9) | 2003 (5.6) | <.001 |
| Median (range) | 2008 (1986-2013) | 2003 (1978-2013) | |
| Tumor diameter,a cm | |||
| Mean (SD) | 1.8 (1.5) | 1.6 (1.1) | .21 |
| Median (IQR) | 1.4 (0.5-9.0) | 1.3 (0.1-8.3) | |
| Anatomic site, No. (%)b | |||
| Face | 222 (80.2) | 141 (36.7) | <.001 |
| Scalp/neck | 23 (8.3) | 26 (6.8) | |
| Trunk | 10 (3.6) | 73 (19.0) | |
| Upper extremity | 13 (4.7) | 85 (22.1) | |
| Lower extremity | 9 (3.2) | 59 (15.4) | |
| WLE surgical margins, mean (SD), cm | NA | 0.6 (0.3) | |
| Recurrences, No. (%) | 5 (1.8) | 22 (5.7) | .07 |
| WLE margin taken, mean (SD), cm | |||
| Recurred | NA | 0.9 (0.2) | .003 |
| Not recurred | NA | 0.6 (0.04) | |
| Time to recurrence, mean (SD), y | 3.91 (4.4) | 4.45 (2.7) | .73 |
| Deaths, No. (%)c | |||
| All cause | 37 (13.4) | 75 (19.5) | |
| Melanoma specific | 2 (0.7) | 13 (3.4) | |
| Time to death, mean (SD), y | |||
| All cause | 18.4 (0.8) | 17.4 (0.4) | .28 |
| Melanoma specific | 6.5 (4.8) | 6.1 (0.8) | .77 |
Abbreviations: IQR, interquartile range; MMS, Mohs micrographic surgery; NA, not applicable; WLE, wide local excision.
a
Preoperative assessment of 107 MMS-treated patients and 74 WLE-treated patients.
b
Assessment of 277 MMS-treated patients and 384 WLE-treated patients.
c
P values not given because a statistical test comparing the raw counts/percentages does not account for differential follow-up time (see time to death analyses).