Official websites use .gov
A
.gov website belongs to an official
government organization in the United States.
Secure .gov websites use HTTPS
A lock (
) or https:// means you've safely
connected to the .gov website. Share sensitive
information only on official, secure websites.
Reagents and conditions: (a) 1 (1 equiv), HCl·NH2-Ala-Tyr-OMe (1 equiv), HOBt (1 equiv), EDC (1.5 equiv), Et3N (3.3 equiv), MeCN/DMF, 25 °C (72%); (b) [Cu(MeCN)4][PF6] (2 equiv), TMEDA (2 equiv), O2, MeCN, then 2 (1 equiv), 25 °C (60%). Abbreviations: HOBt = 1-hydroxybenzotriazole, EDC = N-ethyl-N′-(3-(dimethylamino)propyl)carbodiimide hydrochloride, TMEDA = N,N,N′,N′-tetramethylethylenediamine.
