Table 7.

Gene ontology enrichment on the 182 set of common genes using the tools available at Boyce Thompson Institute, Cornell University (http://bioinfo.bti.cornell.edu/cgi-bin/MetGenMAP/home.cgi).

Gene ontology term	Number of genes	Cluster frequency (%)	Genome frequency (%)	Corrected p-value
Unfolded protein binding	3	1.6	0.2	0.038
Structural molecule activity	11	6.0	0.7	0.000
Structural constituent of ribosome	10	5.5	0.5	0.000
Small molecule binding	16	8.8	3.9	0.028
Small GTPase regulator activity	3	1.6	0.1	0.032
Ribonucleotide binding	11	6.0	2.0	0.025
Purine ribonucleotide binding	11	6.0	2.0	0.023
Purine ribonucleoside triphosphate binding	11	6.0	2.0	0.025
Purine nucleotide binding	11	6.0	2.0	0.021
Protein binding	44	24.2	11.9	0.000
Oxidoreductase activity acting on NADH or NADPH	4	2.2	0.2	0.003
Oxidoreductase activity	16	8.8	2.8	0.000
Organic cyclic compound binding	16	8.8	3.3	0.013
Nucleotide binding	16	8.8	3.3	0.015
Nucleoside phosphate binding	16	8.8	3.3	0.012
Catalytic activity	53	29.1	17.9	0.000
Binding	79	43.4	25.1	0.000
ATP binding	9	4.9	1.4	0.020
Adenyl ribonucleotide binding	9	4.9	1.4	0.019
Adenyl nucleotide binding	9	4.9	1.4	0.020

The table shows the cluster frequency (the 182 genes) compared to the genome frequency for each category with the FDR-corrected p-value. The three categories (structural constituent of ribosomes, small GTPase regulator activity and oxidoreductase activity acting on NADH or NADPH) are where there is the biggest difference between the genome frequency and the cluster frequency.