Figure - PMC

Skip to main content

An official website of the United States government

Here's how you know

Here's how you know

Official websites use .gov
A .gov website belongs to an official government organization in the United States.

Secure .gov websites use HTTPS
A lock ( ) or https:// means you've safely connected to the .gov website. Share sensitive information only on official, secure websites.

View full-text article in PMC

. 2018 Feb 19;17:52. doi: 10.1186/s12943-018-0810-4

Search in PMC
Search in PubMed
View in NLM Catalog
Add to search

© The Author(s). 2018

Open AccessThis article is distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated.

PMC Copyright notice

Fig. 2 — Diagnostic methods for the detection of ALK rearrangement and expression in NSCLC. a FISH: arrows in the upper picture exemplify the split signal pattern, while the ones in the bottom picture specified the single red signal pattern. b IHC using the D5F3 ALK assay. c Diagrammatic representation of full length ALK and the EML4-ALK fusion transcripts indicating ALK domains in the ALK protein, location of ALK RT-PCR primers (black arrows) and the fluorescent probe (green bar) used in the ALK RGQ RT-PCR Kit (Qiagen). TM: transmembrane. d Comparison of two commercially available methods to generate libraries for NGS. a and b adapted from ref. [45]. c reproduced from ref. [42]. d reproduced from ref. [46]