Table 7.
Cytotoxicity of nanostructured CD for mammalian cells (L 929 and Hep G2)
| Formulate | L 929 | HepG2 | ||||
|---|---|---|---|---|---|---|
| 100 µg/mL | 10 µg/mL | 1 µg/mL | 100 µg/mL | 10 µg/mL | 1 µg/mL | |
| CD | 3.4 ± 1 | 2.8 ± 3.1 | 3.4 ± 2.3 | 3.1 ± 3.1 | 3.8 ± 5.6 | 2.7 ± 3.6 |
| CD 12 | 0 ± 0 | 0.8 ± 1.4 | 0.5 ± 0.9 | 0 ± 0 | 0.3 ± 0.6 | 0 ± 0 |
| CD 24 | 1.0 ± 1.8 | 4.2 ± 7.2 | 1.8 ± 3.1 | 0 ± 0 | 0.4 ± 0.6 | 0.3 ± 0.3 |
| CD 52 | 0.4 ± 0.8 | 1.7 ± 1.5 | 3.4 ± 3.0 | 0 ± 0 | 0.1 ± 0.2 | 0.4 ± 0.7 |
ATCC = American Type Culture Collection; CD = cyclodextrin; Hep G2 = human liver hepatocellular cells ATCC; L 929 = murine L-929 fibroblasts (NCTC clone 929); WST = water-soluble tetrazolium test. Data reported as percentage of killed cells (WST test).