Table 1.
Reference standard | ||||||||||
---|---|---|---|---|---|---|---|---|---|---|
1. Active screening (AS) | 2. Passive screening (PS) | AS + PS | ||||||||
Chagas Quick Test® | Test results | Positive | Negative | Total | Positive | Negative | Total | Positive | Negative | Total |
Positive | 194 | 4 | 198 | 18 | 1 | 19 | 212 | 5 | 217 | |
Negative | 43 | 311 | 354 | 1 | 68 | 69 | 44 | 379 | 423 | |
Total | 237 | 315 | 552 | 19 | 69 | 88 | 256 | 384 | 640 | |
CD prev | 42.9% | 21.6% | 40.0% | |||||||
Sensitivity* | 81.9% (77.6–87.2) | 94.7% (73.9–99.9) | 82.8% (77.6–87.2) | |||||||
Specificity* | 98.7% (97.0–99.6) | 99.0% (92.2–99.8) | 98.7% (97.0–99.6) | |||||||
PPV* | 97.7% (94.7–99.0) | 94.7% (72.0–99.2) | 97.7% (94.7–99.0) | |||||||
NPV* | 89.6% (86.8–91.9) | 98.6% (91.0–99.8) | 89.6% (86.8–91.9) |
CD prev = Chagas disease prevalence in the subpopulation.
Sensitivity, Specificity, PPV = positive predictive value, and NPV = negative predictive value expressed as a percentage and 95% CI.