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. 2017 Dec 15;6(1):e00367. doi: 10.1002/prp2.367

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© 2017 The Authors. Pharmacology Research & Perspectives published by John Wiley & Sons Ltd, British Pharmacological Society and American Society for Pharmacology and Experimental Therapeutics.

This is an open access article under the terms of the Creative Commons Attribution‐NonCommercial‐NoDerivs License, which permits use and distribution in any medium, provided the original work is properly cited, the use is non‐commercial and no modifications or adaptations are made.

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Results of behavioral tests in unoperated rats. (A) The number of line crosses in the open‐field test (OFT) in saline, low‐dose and high‐dose groups. (B) The number of rearings and leanings in OFT. (C) The grooming time in OFT. (D) The percentage of time in the closed arm in the elevated plus‐maze test. (E) The percentage of time spent in the light box in the light‐dark box test. (F) Consumption of sucrose‐containing water as a percentage of total water consumption in the sucrose preference test. (G) Locomotion in the rotarod test, measured as the time (s) on the drum (=drop latency). Low dose: 50 mg/kg of paracetamol, High dose: 300 mg/kg of paracetamol. Error bars indicate SEM (n = 6). *P < .05, **P < .01, ***P < .001 (Bonferroni‐corrected t test)