Table 1.

In vivo studies of natural products against hematological malignancies

HSS(Haishengsu)	Nude mice	450,900,1800 mg/kg bw, intravenous	↓Bcr-Abl	[213]
Triptolide	Nu/nu BALB/c mice	0.15 mg/kg Bw, subcutaneous	↓Bcr-Abl	[214]
curcumin	Balb/c mice	40 mg/kg bw, intraperitonial	↓c-ABL	[216]
Berbamine(BBM)	Balb/c	60 mg/kg bw, intravenously	↓p-gp protein	[220]
4-Chlorobenzoyl berbamine(BBD9)	NU−/−	15 and 30 mg/kg BW,	↓P-BCR-ABL	[223]
Tetrandrine citrate	Nu−/−	100 mg/kg BW, orally	↓BCR-ABL	[225]
homoharringtonine	BABL/c mice	0.5–1 mg/kg BW, intraperitonial	↓Bcr-Abl	[186]
Oroxylin A	SCID	80MG/KG BW, intravenously	↓STAT3,p-gp	[227]
chlorogenic acid	Nude mice	25-150 mg/kg bw, intraperitonial	↓Bcr-Abl	[228]
Celastrol	Nu/nu BalB/c Mice	1 mg/kg BW, intraperitonial	↓Bcr-Abl	[229]
Pristimerin	nu/nu BALB/c mice	1 mg/kg Bw, intratumoral	↓Bcr-Abl	[230]
Herbimycin A	Balb/c nude mice	15 μg,intraperitonial	↓abl	[232]