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. 2018 Feb 6;62(1):467–476. doi: 10.3233/JAD-170999

Table 3.

Mean and 95% confidence interval of nAChRs expression (2-ΔΔCt) in OB and EC of young and aged Tg mice respect to age-matched WT

Olfactory Bulb Entorhinal Cortex
Young mice Aged mice p-valuea Young mice Aged mice p-valuea
nAChRα7 5.3 (3.5–8.1) 1.7 (0.8–3.7) 0.016 1.9 (1.1–3.2) 2.2 (1.1–4.7) 0.759
nAChRα4 3.8 (2.7–5.3) 2.0 (1.1–3.5) 0.067 1.4 (0.9–2.3) 1.1 (0.7–1.8) 0.453
nAChRβ2 4.3 (3.5–5.2) 1.4 (0.8–2.6) 0.002 1.6 (1.1–2.4) 1.5 (0.8–2.9) 0.836

at-test for unpaired data Young mice versus Aged mice. Statistically significant comparisons respect to WT are shown in bold character (p < 0.05).