Skip to main content
. Author manuscript; available in PMC: 2019 Jan 20.
Published in final edited form as: Eur J Med Chem. 2017 Nov 28;144:318–329. doi: 10.1016/j.ejmech.2017.11.080

Scheme 2. Synthetic route to 1 and 10.

Scheme 2

a Reagents and conditions: (a) MCPBA, DCM, 80 °C, sealed tube; (b) NaH, DMF and compound 6 for 10a and 10c respectively, or compound 7 for 10b.